Lissoderes longinoi, new species, and L. masneri, new species are described from specimens collected in Costa Rica and Ecuador, respectively. Lissoderes championi Hespenheide is reported for the first time to be associated with Cecropia angustifolia Trécul, and L. cecropiae Hespenheide reported for the first time with C. obtusifolia Bertoloni. The distribution of members of the genus along an elevational transect in Costa Rica is described, and the ecology of their association with the plant genus Cecropia (Cecropiaceae) is reviewed.